VIRUS HIV-1 E ARGENTO COLLOIDALE

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VIRUS HIV-1 E ARGENTO COLLOIDALE

Messaggioda ANTONIO55 » 13/05/2013, 10:01

Qualche giorno fa mentre facevo il solito giro a caccia di info sul web mi sono imbattuto in un articolo molto interessante (un po’ datato in verità) a proposito della possibilità di utilizzare l’Aci per la cura dell’HIV-1 http://www.biomedcentral.com/content/pd ... 55-3-6.pdf

Abstract
The interaction of nanoparticles with biomolecules and microorganisms is an expanding field of research. Within this field, an area that has been largely unexplored is the interaction of metal nanoparticles with viruses. In this work, we demonstrate that silver nanoparticles undergo a sizedependent interaction with HIV-1, with nanoparticles exclusively in the range of 1–10 nm attached to the virus. The regular spatial arrangement of the attached nanoparticles, the center-to-center distance between nanoparticles, and the fact that the exposed sulfur-bearing residues of the glycoprotein knobs would be attractive sites for nanoparticle interaction suggest that silver nanoparticles interact with the HIV-1 virus via preferential binding to the gp120 glycoprotein knobs.
Due to this interaction, silver nanoparticles inhibit the virus from binding to host cells, as demonstrated in vitro.


Da quanto scritto nell’Abstract sembra che le nanoparticelle d’argento interagiscano con il virus HIV-1 tramite un legame preferenziale con la glicoproteina gp120 inibendo il virus ed impedendogli di legarsi alle cellule ospiti.
Sarebbe interessante sapere se dal 2005 ad oggi qualcuno abbia sperimentato in proprio (visto che le case farmaceutiche sono concentrate più su farmaci antivirali sintetici) e abbia ottenuto qualche risultato.
Antonio
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Re: VIRUS HIV-1 E ARGENTO COLLOIDALE

Messaggioda vishe » 27/09/2019, 21:12

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vishe
 
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